Best Western Muscatine / Pearl City Hotel

Set along the Mississippi River, Muscatine offers a unique blend of history, nature, and small-town charm, and Best Western Muscatine / Pearl City Hotel places you right in the center of it all.

Whether you're in town for the Muscatine Riverfront Festival, the Almost Friday Fest, or a scenic drive along the Great River Road, this hotel provides a comfortable and convenient base for exploring eastern Iowa. Guests enjoy spacious rooms with modern amenities including flat-screen TVs, microwaves, mini-fridges, and complimentary Wi-Fi. Start your morning with a hot breakfast, then take a dip in the indoor heated pool or get in a workout at the fitness center. Business travelers benefit from a 24-hour business center and meeting space, while families appreciate the clean, quiet atmosphere and proximity to attractions like the Muscatine Art Center, Discovery Park, and the historic downtown district. Whether you're visiting for a local event, a business trip, or a weekend escape, Best Western Muscatine / Pearl City Hotel delivers a stay that’s both relaxing and connected to the local experience. With thoughtful amenities and a location that makes exploring easy, it’s a smart choice for travelers looking to enjoy Muscatine their way.